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Like humans, benign and malignant tumors occur in dogs’ mouths. Peripheral odontogenic fibromas (POF) are the most common benign tumors while oral melanomas, squamous cell carcinomas, and fibrosarcomas are the most prevalent malignant tumors in dogs. Diagnosis may be performed via fine needle aspiration or biopsy. Spread to mandibular lymph nodes does occur. Fine needle aspiration of the lymph nodes is recommended when malignant tumors are suspected. Tumor staging including laboratory testing as well as CT imaging helps to plan therapy.
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This handout discusses some of the more common forms of oral tumors in pets. Highlighted are Papillomas (“Warts”) and Fibropapillomas, both of wish are caused by viral infection. Clinical signs, diagnostic methods, and treatment options are highlighted.
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Osteosarcoma, or bone cancer, is common in large breed dogs and is very aggressive, with upwards of 90-95% of patients having micrometastasis. Osteosarcoma is very painful. Lameness or a distinct swelling may be noted. Amputation is by far the most common treatment with chemotherapy following surgery. Radiation therapy may also be an option.
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Rarely, ovarian tissue can be left behind when a dog is spayed. This leads to the ongoing secretion of hormones such as estrogen and progesterone that can result in a dog continuing to have a heat cycle. Ovarian remnants are difficult to diagnose, but vaginal cytology combined with hormone testing can be used to confirm the presence of functional ovarian tissue. Surgical treatment is typically recommended to prevent other health conditions from developing.
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Ovarian tumors are quite rare in North American pets, mainly due to routine spaying practices. This handout discusses ovarian tumors in dogs and cats. The various forms of ovarian tumors, clinical signs, diagnosis, treatment, and prognosis of this cancer are outlined.
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Many dogs will instinctively hide their pain as a survival mechanism which in the past, led well-meaning experts to presume that dogs did not feel pain the same way humans do. Although the signs may be subtle, careful observation of a dog’s everyday behaviors will often reveal pain when it is present. These signs may include changes in behavior, mobility, and appetite. Common pain medications include NSAIDs, opioids, and other therapeutics. Your veterinarian will choose the appropriate drugs based on your dog’s specific needs.
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Primary pancreatic tumors are rare in dogs and cats. Exocrine tumors include adenomas and adenocarcinomas, and endocrine tumors include insulinomas, gastrinomas, and glucagonomas. Insulinomas are the most common type of pancreatic tumor, followed by adenocarcinomas. Both tumors are more common in dogs than cats. Large breed dogs and Siamese cats may be predisposed. Insulinomas are usually diagnosed with the finding of hypoglycemia with normal to high insulin on bloodwork and concomitant clinical signs. Adenocarcinomas typically go undetected until the clinical signs of metastasis are evident. For both tumors, diagnostic imaging and exploratory surgery with tumor removal (or biopsy) and histopathology are needed for a definitive diagnosis. Insulinomas can be treated with surgery and chemotherapy. Surgery is possible with adenocarcinomas, but as the cancer is more diffuse and has usually metastasized by the time of diagnosis, the prognosis is poorer. Chemotherapy and radiation therapy are ineffective in the treatment of adenocarcinomas. Given the high rate of metastasis with these tumors, staging is recommended prior to surgery.
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The pancreas is a vital organ that produces enzymes to assist in food digestion and hormones such as insulin, which regulates blood sugar or glucose metabolism. Pancreatitis is inflammation of the pancreas. Common clinical signs include decreased appetite, nausea, vomiting, lethargy, diarrhea, and abdominal pain. Diagnosis is generally made with laboratory testing and/or abdominal ultrasound. Successful pancreatitis management will depend on early diagnosis and prompt medical therapy. The prognosis depends on the severity of the disease and the response to initial therapy.
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Pancreas-specific lipase is a form of lipase produced only in the pancreas and is highly specific to the pancreas. Blood values increase only when there is pancreatic inflammation. A version of the cPLI test can now be used in-clinic (SNAP fPL© from IDEXX). Ideally, the sample should also be sent to the laboratory to get an actual value of cPLI to help with treatment and monitoring.
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Panniculitis is a localized inflammation of the tissues under the skin, causing a firm swelling (nodule) that may ulcerate and drain fluid. It is a common problem in cats and is less common in dogs. There are several causes of panniculitis, but in younger animals with a single lump, the cause is often blunt trauma and, in cats, it is often caused by bite wounds from fighting. An accurate diagnosis relies on the microscopic examination of tissue and the most common treatment is the surgical removal of the lump(s).
